A NEW P65 ISOFORM THAT BIND THE GLUCOCORTICOID HORMONE AND IS EXPRESSED IN INFLAMMATION LIVER DISEASES AND COVID-19

A new p65 isoform that bind the glucocorticoid hormone and is expressed in inflammation liver diseases and COVID-19

Abstract Inflammation is a physiological process whose deregulation causes some diseases including cancer.Nuclear Factor kB (NF-kB) is a family of ubiquitous and inducible transcription factors, in which the p65/p50 heterodimer is the most abundant complex, that play critical roles mainly in inflammation.Glucocorticoid Receptor (GR) is a ligand-act

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Reflections on generating (disjunctive) cuts

We consider the problem of constructing generic supporting hyperplanes to be used within a (branch and) bound-and-cut algorithm.We review some of the properties that these hyperplanes should enjoy.It is generally admitted that they should cut a parasitic point generated during the process.We 14b-ca0013dx argue that the advantages of restricting sup

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